Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expression

1 Jan 2014

Abstract excerpt

BACKGROUND: MicroRNAs (MiRNA) are small non-coding RNAs that regulate gene expression. The aim of this study was to identify miRNAs differentially expressed between mild and moderately emphysematous lung, as well as their functional target mRNAs. Resected lung from patients with COPD undergoing lung cancer surgery was profiled using miRNA (Agilent Human miRNA profiler G4470 V1.01) and mRNA (OperonV2.0)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Obstructive Pulmonary Disease (COPD) Research
Share to Congenital Diaphragmatic Hernia Studies
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24479666
DOI: 10.1186/1471-2164-15-88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-34c is associated with emphysema severity and modulates SERPINE1 expressionPMID 24479666Read ↗

miR-638 regulates gene expression networks associated with emphysematous lung destructionSemantic proximity Read ↗

Integrative genetic and genomic networks identify microRNA associated with COPD and ILDSemantic proximity Read ↗

Expression profiling identifies genes involved in emphysema severitySemantic proximity Read ↗

Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency.Semantic proximity Read ↗

The role of miRNAs in alveolar epithelial cells in emphysemaSemantic proximity Read ↗

Analysis of Age-Specific Dysregulation of miRNAs in Lung Cancer Via Machine learning: Biomarker Identification and Therapeutic Implications in Patients Aged 60 and AboveSemantic proximity Read ↗

Gene Expression Profiling in Patients with Chronic Obstructive Pulmonary Disease and Lung CancerSemantic proximity Read ↗

Overexpression Of hsa-miR-664a-3p Is Associated With Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease Via Targeting FHL1Semantic proximity Read ↗

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.Semantic proximity Read ↗

microRNA–mRNA regulatory networks underlying chronic mucus hypersecretion in COPDSemantic proximity Read ↗

Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases.Semantic proximity Read ↗

Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.