miR-638 regulates gene expression networks associated with emphysematous lung destruction

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by varying degrees of emphysematous lung destruction and small airway disease, each with distinct effects on clinical outcomes. There is little known about how microRNAs contribute specifically to the emphysema phenotype. We examined how genome-wide microRNA expression is altered with regional emphysema severity and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chronic Obstructive Pulmonary Disease (COPD) Research
• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to MicroRNA in disease regulation