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Article

Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility.

American journal of respiratory cell and molecular biology - 1 Dec 2015

Sarker Rim S J, John-Schuster Gerrit, Bohla Alexander, Mutze Kathrin, Burgstaller Gerald, Bedford Mark T, Königshoff Melanie, Eickelberg Oliver, Yildirim Ali Ö

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is characterized by an irreversible loss of lung function and is one of the most prevalent and severe diseases worldwide. A major feature of COPD is emphysema, which is the progressive loss of alveolar tissue. Coactivator-associated arginine methyltransferase-1 (CARM1) regulates histone methylation and the transcription of genes involved in senescence, proliferation,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25906418
DOI: 10.1165/rcmb.2014-0216OC
PMCID: PMC5455466

Genes

CARM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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