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Article

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.

Journal of virology - 1 Apr 2014

Menachery Vineet D, Yount Boyd L, Josset Laurence, Gralinski Lisa E, Scobey Trevor, Agnihothram Sudhakar, Katze Michael G, Baric Ralph S

Abstract excerpt

UNLABELLED: The sudden emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and, more recently, Middle Eastern respiratory syndrome CoV (MERS-CoV) underscores the importance of understanding critical aspects of CoV infection and pathogenesis. Despite significant insights into CoV cross-species transmission, replication, and virus-host interactions, successful therapeutic options for CoVs...

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Source

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Identifiers

PMID: 24478444
DOI: 10.1128/JVI.03571-13
PMCID: PMC3993736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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