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Adult Thymic Epithelium Contains Nonsenescent Label-Retaining Cells

30 Jan 2014

Abstract excerpt

Progress in our understanding of thymic epithelial cell (TEC) renewal and homeostasis is hindered by the lack of markers for TEC progenitors. Stem and progenitor cell populations display remarkable diversity in their proliferative behavior. In some but not all tissues, stemness is associated with quiescence. The primary goal of our study was to discover whether quiescent cells were present in neonatal and adult...

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PMID: 24477909
DOI: 10.4049/jimmunol.1302961

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