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Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus

4 Dec 2017

Abstract excerpt

Thymic aging precedes that of other organs and is initiated by the gradual loss of thymic epithelial cells (TECs). Based on in vitro culture and transplantation assays, recent studies have reported on the presence of thymic epithelial progenitor cells (TEPCs) in young adult mice. However, the physiological role and properties of TEPC populations reported to date remain unclear. Using an in vivo label-retention...

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PMID: 29259606
DOI: 10.3389/fimmu.2017.01717

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