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Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus

1 Aug 2014

Abstract excerpt

Thymic epithelial cells (TECs) are critical for T cell development and self-tolerance but are gradually lost with age. The existence of thymic epithelial progenitors (TEPCs) in the postnatal thymus has been inferred, but their identity has remained enigmatic. Here, we assessed the entire adult TEC compartment in order to reveal progenitor capacity is retained exclusively within a subset of immature thymic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 25131206
DOI: 10.1016/j.celrep.2014.07.029

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