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Article

Rotary bioreactor culture can discern specific behavior phenotypes in Trk-null and Trk-expressing neuroblastoma cell lines.

In vitro cellular & developmental biology. Animal - 1 Mar 2014

Redden Robert A, Iyer Radhika, Brodeur Garrett M, Doolin Edward J

Abstract excerpt

Neuroblastoma is characterized by biological and genetic heterogeneity that leads to diverse, often unpredictable, clinical behavior. Differential expression of the Trk family of neurotrophin receptors strongly correlates with clinical behavior; TrkA expression is associated with favorable outcome, whereas TrkB with unfavorable outcome. Neuroblastoma cells cultured in a microgravity rotary bioreactor...

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Identifiers

PMID: 24477561
DOI: 10.1007/s11626-013-9716-z
PMCID: PMC4243461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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