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Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine

3 Mar 2017

Abstract excerpt

Several years ago, we detected the formation of multicellular spheroids in experiments with human thyroid cancer cells cultured on the Random Positioning Machine (RPM), a ground-based model to simulate microgravity by continuously changing the orientation of samples. Since then, we have studied cellular mechanisms triggering the cells to leave a monolayer and aggregate to spheroids. Our work focused on...

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PMID: 28273809
DOI: 10.3390/ijms18030546

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