Article
Silencing motifs in the Clr2 protein from fission yeast, Schizosaccharomyces pombe.
PloS one - 1 Jan 2014
Steinhauf Daniel, Rodriguez Alejandro, Vlachakis Dimitrios, Virgo Gordon, Maksimov Vladimir, Kristell Carolina, Olsson Ida, Linder Tomas, Kossida Sophia, Bongcam-Rudloff Erik, Bjerling Pernilla
Abstract excerpt
The fission yeast, Schizosaccharomyces pombe, is a well-established model for heterochromatin formation, but the exact sequence of events for initiation remains to be elucidated. The essential factors involved include RNA transcribed from repeated sequences together with the methyltransferase Clr4. In addition, histone deacetylases, like Clr3, found in the SHREC complex are also necessary for transcriptional...
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