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An Integrative CGH, MSI and Candidate Genes Methylation Analysis of Colorectal Tumors

27 Jan 2014

Abstract excerpt

BACKGROUND: Different DNA aberrations processes can cause colorectal cancer (CRC). Herein, we conducted a comprehensive molecular characterization of 27 CRCs from Iranian patients. MATERIALS AND METHODS: Array CGH was performed. The MSI phenotype and the methylation status of 15 genes was established using MSP. The CGH data was compared to two established lists of 41 and 68 cancer genes, respectively, and to CGH...

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Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer
Share to Genomic variations and chromosomal abnormalities

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PMID: 24475022
DOI: 10.1371/journal.pone.0082185

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