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Article

Genomic Aberrations in an African American Colorectal Cancer Cohort Reveals a MSI-Specific Profile and Chromosome X Amplification in Male Patients

6 Aug 2012

Abstract excerpt

OBJECTIVE: DNA aberrations that cause colorectal cancer (CRC) occur in multiple steps that involve microsatellite instability (MSI) and chromosomal instability (CIN). Herein, we studied CRCs from AA patients for their CIN and MSI status. EXPERIMENTAL DESIGN: Array CGH was performed on 30 AA colon tumors. The MSI status was established. The CGH data from AA were compared to published lists of 41 TSG and oncogenes...

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Share to Colorectal Cancer Screening and Detection
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PMID: 22879877
DOI: 10.1371/journal.pone.0040392

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