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Article

Association between SNPs in P53 binding regions and risk of esophageal squamous cell carcinoma.

The International journal of biological markers - 25 Jun 2014

Wang Kai, Liu Botao, Li Juan, Xiong Gang, Guan Xingying, Yang Kang, Bai Yun

Abstract excerpt

BACKGROUND: The tumor protein 53 (TP53 or p53) plays an important role in tumor suppression by binding to the regulatory region of its target genes. Single nucleotide polymorphisms (SNP) located in the p53 binding regions are likely to affect the expression of p53 target genes and may contribute...

Read the complete abstract on PubMed

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Share to Binding Sites
Share to Carcinoma, Squamous Cell
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Squamous Cell Carcinoma

Share to Genes, p53

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 24474449
DOI: 10.5301/jbm.5000061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24474449-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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