Article
A genetic polymorphism at miR-526b binding-site in the lincRNA-NR_024015 exon confers risk of esophageal squamous cell carcinoma in a population of North China.
Molecular carcinogenesis - 1 Mar 2017
Han Lijie, Liu Shengnan, Liang Jia, Guo Yanli, Shen Supeng, Guo Xin, Dong Zhiming, Guo Wei
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) may be caused by a combination of environmental factors and genetic variants. The present study was to evaluate the association between haplotype-tagging SNPs (htSNPs) of lincRNA-NR_024015 and the risk of ESCC. We selected htSNPs across the whole 1469 bp lincRNA-NR_024015 locus and 2 kb upstream as well as 2 kb downstream regions of the gene and conducted a case-control...
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