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Article

Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma

26 Jan 2014

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) is one of the most aggressive human tumors, and the establishment of an effective therapeutic reagent is a pressing priority. Recently, it has been shown that the tumor tissue consists of heterogeneous components and that a highly aggressive population should be the therapeutic target. METHODS: Through a single subcutaneous passage of GBM cell lines LN443 and U373 in...

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PMID: 24470554
DOI: 10.1093/neuonc/not315

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