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Article

Early growth response 1 promoted the invasion of glioblastoma multiforme by elevating HMGB1.

Journal of neurosurgical sciences - 1 Aug 2023

DU Kai, Wu Xiaoyou, Ji Xiaofei, Liang Nan, Li Zheng

Abstract excerpt

BACKGROUND: Glioblastoma multiforme (GBM) is the most common and deadly glioma subtype. Early growth response 1 (EGR1) participates in the progression of several cancer types, but the expression and function of EGR1 in GBM was rarely investigated. METHODS: The expressions of EGR1 in GBM were detected with qRT-PCR and immunohistochemistry in 12 pairs of fresh GBM tissues and 116 paraffin-embedded specimens. The...

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Source

Identifiers

PMID: 33297605
DOI: 10.23736/S0390-5616.20.05107-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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