Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of ABCB1 and CYP450 Gene Polymorphisms and their DNA Methylation Status with Steroid-Induced Osteonecrosis of the Femoral Head in the Chinese Population.

Genetic testing and molecular biomarkers - 1 Dec 2020

Huang Ronglan, Zhan Qinghao, Hu Wenbin, Yang Renmin, Cheng Nan, Han Yongsheng, Yue Xiuyu

Abstract excerpt

Objective: Osteonecrosis of the femoral head (ONFH) is a severe pathological state with multiple etiologies. Steroid hormone metabolism-related genes play an important role in ONFH. The aim of this study was to investigate the relationships between polymorphisms of the drug-metabolizing enzyme gene, cytochrome P450 (CYP450), and the drug transporter gene, ATP-binding cassette subfamily B member 1 (ABCB1), as well...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Hormones
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to Cytochrome P-450 CYP3A

Share to DNA Methylation

Share to Ethnicity

Share to Femur Head Necrosis

Share to Prednisone

Source

Open in PubMed Open full text

Identifiers

PMID: 33252269
DOI: 10.1089/gtmb.2020.0201
PMCID: PMC7755856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of ABCB1 and CYP450 Gene Polymorphisms and their DNA Methylation Status with Steroid-Induced Osteonecrosis of the Femoral Head in the Chinese Population.PMID 33252269Read ↗

Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population.Semantic proximity Read ↗

Genetic polymorphisms of CYP3A4 among Chinese patients with steroid-induced osteonecrosis of the femoral head.Semantic proximity Read ↗

Genetic analysis of steroid-induced osteonecrosis of the femoral head.Semantic proximity Read ↗

Association between Genetic Polymorphisms of MIR3142HG and the Risk of Steroid-Induced Osteonecrosis of the Femoral Head in the Population of Northern China.Semantic proximity Read ↗

Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population.Semantic proximity Read ↗

DNA methylation in the OPG/RANK/RANKL pathway is associated with steroid-induced osteonecrosis of the femoral headSemantic proximity Read ↗

Combination Analysis of NR3C1, MTHFR and IGFBP3 Gene Polymorphisms and DNA Methylation With Steroid-induced Osteonecrosis of the Femoral Head Risk in Chinese Han Population Semantic proximity Read ↗

Association between genetic polymorphisms of MMP8 and the risk of steroid-induced osteonecrosis of the femoral head in the population of northern China.Semantic proximity Read ↗

DNA Methylation in OPG/RANK/RANKL Pathway is Associated with Steroid-induced Osteonecrosis of the Femoral HeadSemantic proximity Read ↗

ABCB1 polymorphisms associated with osteonecrosis of the femeral head.Semantic proximity Read ↗

Association Between Genetic Polymorphisms of MIR3142HG and the Risk of Steroid-induced Osteonecrosis of the Femoral Head in the Population of Northern ChinaSemantic proximity Read ↗

Integrative analyses of genes related to femoral head osteonecrosis: an umbrella review of systematic reviews and meta-analyses of observational studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.