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Article

Association of ABCB1 C3435T polymorphism with the susceptibility to osteonecrosis of the femoral head: A meta-analysis.

Medicine - 1 May 2017

Zhang Yu, Xie Hui, Zhao Dewei, Wang Benjie, Yang Lei, Meng Qingyu

Abstract excerpt

BACKGROUND AND OBJECTIVE: The exploration for the etiology of osteonecrosis of the femoral head (ONFH) has got some promising findings, but the morbidity of ONFH is still not under control. The C3435T polymorphism of ATP-binding cassette subfamily B member 1 (ABCB1) gene has been reported to possess significant influence on ONFH onset, but relevant outcomes remain conflicting rather than conclusive. Therefore, a...

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Identifiers

PMID: 28514285
DOI: 10.1097/MD.0000000000006049
PMCID: PMC5440122

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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