Article
MDR1(ABCB1) gene polymorphisms associated with steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus.
Die Pharmazie - 1 Dec 2007
Yang X Y, Xu D H
Abstract excerpt
This study investigated the relationship between genetic polymorphism in the MDR1 (C3435T, G2677T) and the development of steroid-induced osteonecrosis of femoral head (ONF) in Chinese systemic lupus erythematosus (SLE) patients. 127 patients with active SLE, receiving 40 mg/day or more prednisolone were included. Patients were observed for the development of ONF by magnetic resonance imaging (MRI) and plain...
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