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Article

Association between Genetic Polymorphisms of MIR3142HG and the Risk of Steroid-Induced Osteonecrosis of the Femoral Head in the Population of Northern China.

Public health genomics - 1 Jan 2022

Wang Tiantian, Wu Huiqiang, Sun Menghu, Liu Tingting, An Feimeng, Dong Qiumei, Wang Jianzhong

Abstract excerpt

BACKGROUND: Steroid-induced osteonecrosis of the femoral head (ONFH) is aseptic necrosis of the femoral head caused by glucocorticoid use. Once necrotic femoral head necrosis occurs, it irreversibly affects the quality of life seriously. Studies have shown that the susceptibility to steroid-induced ONFH is likely to be related to the variation of miRNA-coding genes. Therefore, this study aimed was to investigate...

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PMID: 34788764
DOI: 10.1159/000519577

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