Article
Expression and functional characterization of Smyd1a in myofibril organization of skeletal muscles.
PloS one - 1 Jan 2014
Gao Jie, Li Junling, Li Bao-Jun, Yagil Ezra, Zhang Jianshe, Du Shao Jun
Abstract excerpt
BACKGROUND: Smyd1, the founding member of the Smyd family including Smyd-1, 2, 3, 4 and 5, is a SET and MYND domain containing protein that plays a key role in myofibril assembly in skeletal and cardiac muscles. Bioinformatic analysis revealed that zebrafish genome contains two highly related smyd1 genes, smyd1a and smyd1b. Although Smyd1b function is well characterized in skeletal and cardiac muscles, the...
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