Article
A genome-wide association study identifies a locus on TERT for mean telomere length in Han Chinese.
PloS one - 1 Jan 2014
Liu Yun, Cao Lan, Li Zhiqiang, Zhou Daizhan, Liu Wanqing, Shen Qin, Wu Yanting, Zhang Dan, Hu Xun, Wang Ting, Ye Junyi, Weng Xiaoling, Zhang Hong, Zhang Di, Zhang Zhou, Liu Fatao, He Lin, Shi Yongyong
Abstract excerpt
Leukocyte telomere length (LTL) is a predictor of aging and a number of age-related diseases. We performed genome-wide association studies of mean LTL in 2632 individuals,with a two-stage replication in 3917 individuals from Chinese populations. To further validate our findings, we get the results of 696 samples from a cohort of European ancestry. We identified two loci associated with LTL that map in telomerase...
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