Article
Polymorphisms in Telomere Length Associated TERC and TERT predispose for Ischemic Stroke in a Chinese Han population.
Scientific reports - 6 Jan 2017
Zhang Shuo, Ji Guofa, Liang Yiqian, Zhang Rui, Shi Puyu, Guo Dangshe, Li Chunqi, Feng Jing, Liu Feng, Peng Rong, Chen Mingwei
Abstract excerpt
The role of telomere in genomic stability is an established fact. Variation in leukocyte telomere length (LTL) has been considered a crucial factor that associated with age-associated diseases. To elucidate the association between LTL variation and ischemic stroke (IS) risk, we selected ten single nucleotide polymorphisms (SNPs) in three genes (TERC, TERT and RTEL1) that previously reported link to LTL, and...
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