Article
Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal.
Journal of medical genetics - 1 Jan 2018
Delgado Dayana A, Zhang Chenan, Chen Lin S, Gao Jianjun, Roy Shantanu, Shinkle Justin, Sabarinathan Mekala, Argos Maria, Tong Lin, Ahmed Alauddin, Islam Tariqul, Rakibuz-Zaman Muhammad, Sarwar Golam, Shahriar Hasan, Rahman Mahfuzar, Yunus Mohammad, Jasmine Farzana, Kibriya Muhammad G, Ahsan Habibul, Pierce Brandon L
Abstract excerpt
BACKGROUND: Leucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. Leucocyte TL is heritable and shows substantial differences by race/ethnicity. Recent genome-wide association studies (GWAS) report ~10 loci harbouring SNPs associated with leucocyte TL, but these studies focus primarily on populations of European ancestry. OBJECTIVE: This study aims to enhance our...
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