Article
The clarifying role of time series data in the population genetics of HIV.
PLoS genetics - 1 Jan 2021
Feder Alison F, Pennings Pleuni S, Petrov Dmitri A
Abstract excerpt
HIV can evolve remarkably quickly in response to antiretroviral therapies and the immune system. This evolution stymies treatment effectiveness and prevents the development of an HIV vaccine. Consequently, there has been a great interest in using population genetics to disentangle the forces that govern the HIV adaptive landscape (selection, drift, mutation, and recombination). Traditional population genetics...
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