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Article

Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae.

Cell stress & chaperones - 1 Sept 2014

Saleh Aliabbas A, Bhadra Ankan Kumar, Roy Ipsita

Abstract excerpt

Formation of cytoplasmic and nuclear aggregates is a hallmark of Huntington's disease (HD). Inhibition of aggregation of mutant huntingtin has been suggested to be a feasible approach to slow down the progress of this neurodegenerative disorder. Exposure to environmental stimuli leads to the activation of the stress response machinery of the cell. In this work, we have investigated the effect of salt shock on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24464493
DOI: 10.1007/s12192-014-0492-9
PMCID: PMC4147074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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