Article
Protein aggregation activates erratic stress response in dietary restricted yeast cells.
Scientific reports - 16 Sept 2016
Bhadra Ankan Kumar, Das Eshita, Roy Ipsita
Abstract excerpt
Chronic stress and prolonged activation of defence pathways have deleterious consequences for the cell. Dietary restriction is believed to be beneficial as it induces the cellular stress response machinery. We report here that although the phenomenon is beneficial in a wild-type cell, dietary restriction leads to an inconsistent response in a cell that is already under proteotoxicity-induced stress. Using a yeast...
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