Article
Measuring competitive fitness in dynamic environments.
The journal of physical chemistry. B - 24 Oct 2013
Razinkov Ivan A, Baumgartner Bridget L, Bennett Matthew R, Tsimring Lev S, Hasty Jeff
Abstract excerpt
Most yeast genes are dispensable for optimal growth in laboratory cultures. However, this apparent lack of fitness contribution is difficult to reconcile with the theory of natural selection. Here we use stochastic modeling to show that environmental fluctuations can select for a genetic mechanism that does not affect growth in static laboratory environments. We then present a novel experimental platform for...
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