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Article

Mannose binding lectin and ficolin-2 polymorphisms are associated with increased risk for bacterial infections in children with B acute lymphoblastic leukemia.

Pediatric blood & cancer - 1 Jun 2014

Pana Zoe Dorothea, Samarah Fekri, Papi Rigini, Antachopoulos Charalampos, Papageorgiou Theodotis, Farmaki Evangelia, Hatzipantelis Emmanuel, Tragiannidis Athanassios, Vavatsi-Christaki Norma, Kyriakidis Dimitrios, Athanassiadou-Piperopoulou Fani, Roilides Emmanuel

Abstract excerpt

BACKGROUND: We aimed to investigate whether the presence of mannose binding lectin (MBL2), ficolin 2 (FCN2) polymorphisms or the combined deficiency significantly influence the risk and subsequently the frequency of chemotherapy-induced bacterial infections in children with B acute lymphoblastic leukemia (B-ALL). PROCEDURE: MBL2 polymorphisms for exon 1 and FCN2 polymorphisms for promoter regions -986, -602,...

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Topics

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Share to Bacterial Infections
Share to Ficolins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to Immunocompromised Host

Share to Lectins

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Share to Metabolism, Inborn Errors

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 24453114
DOI: 10.1002/pbc.24951

Genes

FCN2
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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