Article
Deficiency of mannose-binding lectin and burden of infection in children with malignancy: a prospective study.
Lancet (London, England) - 25 Aug 2001
Neth O, Hann I, Turner M W, Klein N J
Abstract excerpt
BACKGROUND: Infection is a major cause of morbidity and mortality in children with malignancy. Individuals with serum deficient in mannose-binding lectin (MBL)-an important component of the innate immune system-are more susceptible to infection than those with adequate concentrations. In this study, we investigated the capacity of this protein to influence infectious complications in children undergoing treatment...
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