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Article

Clinical Implication of Toll-Like Receptors (TLR2 and TLR4) Polymorphisms in Adult Patients with Acute B-cell Lymphoblastic Leukemia.

Asian Pacific journal of cancer prevention : APJCP - 1 Mar 2022

Aref Salah, Abdelmaksoud Alshaimaa, Abdellaziz Sherin, Al Tantawy Ahmed, Mabed Mohamed, Atia Doaa

Abstract excerpt

BACKGROUNDS: Neutropenia after intensive chemotherapy of acute lymphoblastic leukemia (ALL) could lead to infectious complications that affect outcome of acute leukemia patients. Many single-nucleotide polymorphisms (SNPs) of Toll-like receptors (TLRs) can affect the genetic susceptibility to infections. We investigated the impact of different SNPs on the incidence of developing sepsis and pneumonia in patients...

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Identifiers

PMID: 35345353
DOI: 10.31557/APJCP.2022.23.3.823
PMCID: PMC9360939

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