Article
Infections during induction therapy of childhood acute lymphoblastic leukemia--no association to mannose-binding lectin deficiency.
European journal of haematology - 1 Jun 2006
Lausen Birgitte, Schmiegelow Kjeld, Andreassen Bente, Madsen Hans O, Garred Peter
Abstract excerpt
OBJECTIVES: Infection during the induction phase of childhood acute lymphoblastic leukemia (ALL) is a major cause of morbidity and mortality. Several studies have indicated that genetically determined low serum levels of mannose-binding lectin (MBL), a component of innate immunity, are associated with increased risk for infections in patients receiving chemotherapy. Thus, these patients have been proposed to be...
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