Article
Increased frequency of mannose-binding lectin insufficiency among children with acute lymphoblastic leukemia.
Blood - 15 Nov 2002
Schmiegelow Kjeld, Garred Peter, Lausen Birgitte, Andreassen Bente, Petersen Bodil Laub, Madsen Hans Ole
Abstract excerpt
Epidemiological data indicate that acute lymphoblastic leukemia (ALL) could be induced by interactions between the immune system and early childhood infections. Mannose-binding lectin (MBL) plays a critical role in the immune response in early childhood before specific immune protection develops. We investigated whether there may be an association between childhood ALL and low-producing MBL genotypes. Serum MBL...
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