Article
Differential selection in HIV-1 gp120 between subtype B and East Asian variant B'.
Virologica Sinica - 1 Feb 2014
Dang Stefan, Wang Yan, Budeus Bettina, Verheyen Jens, Yang Rongge, Hoffmann Daniel
Abstract excerpt
HIV-1 evolves strongly and undergoes geographic differentiation as it spreads in diverse host populations around the world. For instance, distinct genomic backgrounds can be observed between the pandemic subtype B, prevalent in Europe and North-America, and its offspring clade B' in East Asia. Here we ask whether this differentiation affects the selection pressure experienced by the virus. To answer this question...
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