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Article

Positive selection signals of hepatitis B virus and their association with disease stages and viral genotypes.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2013

Xu Zhe, Wu Guanghua, Li Feifei, Bai Jian, Xing Wanjin, Zhang Dake, Zeng Changqing

Abstract excerpt

The hepatitis B virus (HBV) is a global health problem that causes different types of liver diseases. The high mutation rate of HBV, which results from a lack of proofreading activity of the viral polymerase, leads to the actively adaptive evolution of mutant strains under various selection pressures. This study focuses on the positive selection signals in the whole HBV genome and the association of these...

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Identifiers

PMID: 23871771
DOI: 10.1016/j.meegid.2013.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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