Article
Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome.
Journal of gastroenterology and hepatology - 1 Jun 2014
Jiang Yingjie, Nie Yuqiang, Li Yuyuan, Zhang Long
Abstract excerpt
BACKGROUND AND AIM: The endocannabinoid system is involved in the pathophysiology of irritable bowel syndrome (IBS). Here, we investigated whether genetic variants of the cannabinoid type 1 receptor (CNR1) and fatty acid amide hydrolase (FAAH) are associated with the pathogenesis of IBS. METHODS: In total, 292 patients with IBS and 298 healthy controls were enrolled. Polymerase chain reaction (PCR) and DNA...
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