Article
Cannabinoid receptor 1 gene polymorphism and irritable bowel syndrome in the Korean population: a hypothesis-generating study.
Journal of clinical gastroenterology - 1 Jan 2011
Park Jae Myung, Choi Myung-Gyu, Cho Yu Kyung, Lee In Seok, Kim Sang Woo, Choi Kyu Yong, Chung In-Sik
Abstract excerpt
OBJECTIVE: The cannabinoids affect gastrointestinal function and are thought to be involved in the pathogenesis of irritable bowel syndrome (IBS). We hypothesized that genetic variants of the cannabinoid receptor 1 gene (CNR1) might be associated with IBS. METHODS: One hundred sixty-two IBS patients, who met the Rome II criteria, and 423 healthy controls were subjected to genotyping of polymorphic triplet AAT...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
