Article
Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity.
Neurogastroenterology and motility - 1 Jul 2011
Vazquez-Roque M I, Camilleri M, Vella A, Carlson P, Laugen J, Zinsmeister A R
Abstract excerpt
BACKGROUND: The endocannabinoid system is associated with food intake. We hypothesized that genes regulating cannabinoids are associated with obesity. Genetic variations in fatty acid amide hydroxylase (FAAH) and cannabinoid receptor 1 (CNR1) are associated with satiation and gastric motor function. METHODS: In 62 overweight or obese adults of European ancestry, single nucleotide polymorphisms of rs806378...
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