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Article

The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.

PloS one - 26 Feb 2010

Storr Martin, Emmerdinger Dominik, Diegelmann Julia, Pfennig Simone, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Brand Stephan

Abstract excerpt

BACKGROUND: Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide polymorphism (SNP) on disease suscept...

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Source

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Identifiers

PMID: 20195480
DOI: 10.1371/journal.pone.0009453
PMCID: PMC2829088

Genes

CNR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20195480-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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