Cannabinoid receptor 1 gene and irritable bowel syndrome: phenotype and quantitative traits.

doi:10.1152/ajpgi.00376.2012

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Cannabinoid receptor 1 gene and irritable bowel syndrome: phenotype and quantitative traits.

American journal of physiology. Gastrointestinal and liver physiology - 1 Mar 2013

Camilleri Michael, Kolar Gururaj J, Vazquez-Roque Maria I, Carlson Paula, Burton Duane D, Zinsmeister Alan R

Abstract excerpt

Genetic variations in metabolism of endocannabinoids and in CNR1 (gene for cannabinoid 1 receptor) are associated with symptom phenotype, colonic transit, and left colon motility in irritable bowel syndrome (IBS). Our aim was to evaluate associations between two variations in CNR1 genotype (rs806378 and [AAT]n triplets) with symptom phenotype, small bowel and colonic transit, and rectal sensations in 455 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Demography

Share to Genotype

Share to Irritable Bowel Syndrome

Share to Pressure

Share to Receptor, Cannabinoid, CB1

Share to Rectum

Share to Trinucleotide Repeats

Source

Open in PubMed Open full text

Identifiers

PMID: 23306084
DOI: 10.1152/ajpgi.00376.2012
PMCID: PMC3602676

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cannabinoid receptor 1 gene and irritable bowel syndrome: phenotype and quantitative traits.PMID 23306084Read ↗

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation.Semantic proximity Read ↗

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome.Semantic proximity Read ↗

Genetics of human gastrointestinal sensation.Semantic proximity Read ↗

Pharmacogenetic trial of a cannabinoid agonist shows reduced fasting colonic motility in patients with nonconstipated irritable bowel syndrome.Semantic proximity Read ↗

Cannabinoid receptor 1 gene polymorphism and irritable bowel syndrome in the Korean population: a hypothesis-generating study.Semantic proximity Read ↗

Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea.Semantic proximity Read ↗

Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome.Semantic proximity Read ↗

The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.Semantic proximity Read ↗

Genetics and gastrointestinal symptoms.Semantic proximity Read ↗

Genetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretion.Semantic proximity Read ↗

Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders.Semantic proximity Read ↗

Association of genetic variation in cannabinoid mechanisms and gastric motor functions and satiation in overweight and obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.