Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of VEGF, TGFβ1, TGFβR2 and conotruncal heart defects in a Chinese population.

Molecular biology reports - 1 Mar 2014

Wang Enshi, Wang Zhenhua, Liu Shenghua, Gu Haiyong, Gong Dingxu, Hua Kun, Nie Yu, Wang Jue, Wang Haoran, Gong Jie, Zhang YuJian, Zhang Hui, Liu Ruiping, Hu Shengshou, Zhang Hao

Abstract excerpt

Genetic variants may determine susceptibility of congenital heart disease (CHD). To evaluate the impact of transforming growth factor-β1 (TGFβ1), TGFβ receptor II (TGFβR2) and vascular endothelial growth factor (VEGF) polymorphisms on conotruncal heart defects susceptibility, we genotyped six functional polymorphisms TGFβ1 rs1800469 C>T, TGFβR2 rs3087465 G>A, VEGF -2578C>A, -1498T>C, -634G>C and +936C>T in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population
Share to Heart Defects, Congenital
Share to Protein Serine-Threonine Kinases
Share to Receptor, Transforming Growth Factor-beta Type II
Share to Receptors, Transforming Growth Factor beta
Share to Tetralogy of Fallot
Share to Transforming Growth Factor beta1
Share to Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 24443223
DOI: 10.1007/s11033-014-3025-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of VEGF, TGFβ1, TGFβR2 and conotruncal heart defects in a Chinese population.PMID 24443223Read ↗

Genetic variance of transforming growth factor β2 gene in conotruncal heart defects.Semantic proximity Read ↗

The genotype and expression of the TGFβ2 gene in children with congenital conotruncal defects.Semantic proximity Read ↗

Association between TGFBR2 gene polymorphisms and congenital heart defects in Han Chinese population.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and reduced folate carrier 80 G>A polymorphisms are associated with an increased risk of conotruncal heart defects.Semantic proximity Read ↗

Association of growth/differentiation factor 1 gene polymorphisms with the risk of congenital heart disease in the Chinese Han population.Semantic proximity Read ↗

Mutations in fibroblast growth factor (FGF8) and FGF10 identified in patients with conotruncal defects.Semantic proximity Read ↗

Intronic Polymorphisms in Gene of Second Heart Field as Risk Factors for Human Congenital Heart Disease in a Chinese PopulationSemantic proximity Read ↗

Characterization of nodal/TGF-lefty signaling pathway gene variants for possible roles in congenital heart diseases.Semantic proximity Read ↗

Association of TGFBR2 rs6785358 Polymorphism with Increased Risk of Congenital Ventricular Septal Defect in a Chinese Population.Semantic proximity Read ↗

Analyses of GATA4, NKX2.5, and TFAP2B genes in subjects from southern China with sporadic congenital heart disease.Semantic proximity Read ↗

[Association between rs6658835 polymorphism of transforming growth factor beta 2 gene and congenital heart diseases in Chinese Han population].Semantic proximity Read ↗

Association between MTHFR C677T Variant and Risk for Conotruncal Heart Defects in Egyptian Children: A Meta-analysis based on 217 cases and 213 controlsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.