Article
Genetic variance of transforming growth factor β2 gene in conotruncal heart defects.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000
Chen Yu, Zhang Rui, Xie Jun, Li Yajiao, Shi Shaoqing, Qian Hong, Yan Zhiguo, Rao Li
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate the association between two haplotype-tag single nucleotide polymorphisms (SNPs) (rs6658835 and rs10495098) of TGF-β2 and conotruncal heart defects (CTDs). METHODS: Two polymorphisms of TGF-β2 gene were genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) from 259 CTDs patients and 310 control subjects. RESULTS: The association...
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