Association of growth/differentiation factor 1 gene polymorphisms with the risk of congenital heart disease in the Chinese Han population.

doi:10.1007/s11033-012-2172-0

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Article

Association of growth/differentiation factor 1 gene polymorphisms with the risk of congenital heart disease in the Chinese Han population.

Molecular biology reports - 1 Feb 2013

Sun Xiaowei, Meng Ying, You Tao, Li Peiqiang, Wu Hua, Yu Ming, Xie Xiaodong

Abstract excerpt

There is evidence suggesting that genetic variants of Nodal signaling may be associated with risk of congenital heart diseases (CHDs), in which several polymorphisms, such as Nodal rs1904589, have been considered to be implicated in the accumulation of the genetic burden of CHD risk with interacting genes. We hypothesized that genetic variants of GDF1, a protein that heterodimerizes with Nodal, may be related to...

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PMID: 23076529
DOI: 10.1007/s11033-012-2172-0

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GDF1

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