Article
Analytical performance of the cobas EGFR mutation assay for Japanese non-small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2014
Kimura Hideharu, Ohira Tatsuo, Uchida Osamu, Matsubayashi Jun, Shimizu Shinichiro, Nagao Toshitaka, Ikeda Norihiko, Nishio Kazuto
Abstract excerpt
INTRODUCTION: Clinical outcomes in non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations have been reported to be correlated with the use of EGFR-tyrosine kinase inhibitors (EGFR-TKIs). Therefore, it is essential to confirm the presence of EGFR mutations using highly sensitive testing methods. In this study, we compared the performance of the cobas(®) EGFR Mutation...
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