Article
Detection of epidermal growth factor receptor gene T790M mutation in cytology samples using the cobas® EGFR mutation test.
Lung cancer (Amsterdam, Netherlands) - 1 Sept 2017
Satouchi Miyako, Tanaka Hiroshi, Yoshioka Hiroshige, Shimokawaji Tadasuke, Mizuno Keiko, Takeda Koji, Yoshino Ichiro, Seto Takashi, Kurata Takayasu, Tashiro Naoki, Hagiwara Koichi
Abstract excerpt
OBJECTIVE: Detection of epidermal growth factor receptor (EGFR) gene mutations is essential in deciding therapeutic strategy in non-small cell lung cancer (NSCLC) patients at initial diagnosis. Moreover, in EGFR mutation-positive (EGFRm) NSCLC patients, re-biopsy at disease progression to clarify resistance mechanisms is also important. However, collecting histology samples is often difficult because of...
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