Article
Accuracy of the cobas EGFR Mutation Assay in Non-small-cell Lung Cancer Compared With Three Laboratory-developed Tests.
Clinical lung cancer - 1 Mar 2018
Nakamura Haruhiko, Koizumi Hirotaka, Sakai Hiroki, Kimura Hiroyuki, Miyazawa Tomoyuki, Marushima Hideki, Saji Hisashi, Takagi Masayuki
Abstract excerpt
BACKGROUND: The reliability of the cobas EGFR assay to detect epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC) as an in vitro diagnostic test was compared with 3 laboratory-developed tests (LDTs). MATERIALS AND METHODS: After screening for EGFR mutations using formalin-fixed-paraffin-embedded NSCLC tissue sections using the cobas EGFR assay, 151 samples were further tested...
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