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Article

The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2014

Jensen Kevin P, Kranzler Henry R, Stein Murray B, Gelernter Joel

Abstract excerpt

Functional variants that contribute to genomewide association study (GWAS) signals are difficult to identify. MicroRNAs could contribute to some of these gene-trait relationships. We compiled a set of GWAS trait gene SNPs that were predicted to affect microRNA regulation of mRNA. Trait associations were tested in a sample of 6725 European-American (EA) and African-American (AA) subjects that were interviewed...

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Identifiers

PMID: 24436253
DOI: 10.1002/ajmg.b.32219
PMCID: PMC4174417

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