Article
MicroRNA-Related Polymorphism and Their Association with Fibromyalgia.
Genes - 21 Jun 2023
Berg Fabian, Moser Dirk A, Hagena Verena, Streit Fabian, Mosch Benjamin, Kumsta Robert, Herpertz Stephan, Diers Martin
Abstract excerpt
MicroRNAs are tissue-specific expressed short RNAs that serve post-transcriptional gene regulation. A specific microRNA can bind to mRNAs of different genes and thereby suppress their protein production. In the context of the complex phenotype of fibromyalgia, we used the Axiom miRNA Target Site Genotyping Array to search genome-wide for DNA variations in microRNA genes, their regulatory regions, and in the 3'UTR...
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