Article

Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia

2024-12-30

Abstract excerpt

Benign prostatic hyperplasia (BPH) is among the most common age-associated diseases in men; however, the contribution of age-related changes in immune cells to BPH is not clear. The current study determined that an age-associated CD8 + T cell subset (Taa) with high Granzyme K ( GZMK hi ) and low Granzyme B ( GZMB low ) gene expression infiltrate aged human prostates and positively correlate with International...

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Literature Corpus work: d3bd08ab-3cab-5925-9f52-cd2391c0988a
DOI: 10.1101/2024.12.30.629739

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