Article
Prp4 kinase is required for proper segregation of chromosomes during meiosis in Schizosaccharomyces pombe.
Acta biochimica Polonica - 1 Jan 2013
Pozgajova Miroslava, Cipak Lubos, Trakovicka Anna
Abstract excerpt
Chromosome segregation during meiosis is a complex process, which leads to production of four haploid gametes from two precursor cells. Reversible phosphorylation of proteins plays a crucial role in this process. The Schizosaccharomyces pombe Prp4 is an essential serine/threonine protein kinase, which belongs to the Clk/Sty family. To study the role of Prp4 in meiosis, we analysed chromosome segregation in a...
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